Chemistries

Natrix technology is available in both Ion Exchange and Affinity Chemistries

Ion Exchange Chemistry

• Strong Anion Exchange Membranes (Q)
  • High binding capacity for negatively-charged proteins and large biomolecules such as DNA, viruses and plasmids
  • The Q chemistry is well suited to polishing applications
• Strong and Weak Cation Exchange Membranes (S and C)
  • High binding capacities for positively-charged proteins, salts and metal ions
  • The S and C chemistries are ideal for use in purification/primary capture of recombinant proteins
  • Weak cation exchange membrane binds positively-charged proteins and antibodies and is very effective for use in antibody capture applications

Affinity

• Available in a variety of Affinity formulations
  • Protein A: for the purification of antibodies
  • IMAC-Ni Membranes: for the purification of His-tagged proteins

Functionalized (Aldehyde Chemistry)

• For custom derivatization by end users with their own proprietary ligands